The Cracking Cancer Podcast
Join Dr. Kyle Concannon, an MD Anderson–trained cancer doctor and scientist, together with the patient community, as we break down the knowledge and cultural barriers between cancer patients and cancer providers. Cracking Cancer empowers listeners with clear, accessible insights into cancer care, treatment options, and the complex world of cancer. Here, academic experts (providers) and experiential experts (patients) come together to discuss critical topics and build a more informed, supportive cancer community. Join us as we crack the code to better communication, knowledge, and collaboration in the fight against cancer. This podcast is intended for informational purposes only. It does not constitute medical advice and should not be relied upon as such. The views expressed are those of the participants and not of their affiliated organizations.
Episodes

Thursday Aug 28, 2025
Thursday Aug 28, 2025
Welcome to a powerful new episode of "Cracking Cancer," where hosts Dr. Kyle Concannon and patient advocate Samantha Murrell pull back the curtain on the complex world of cancer research. In this candid discussion, they tackle the fundamental questions you've always wanted to ask:
Who are the key players in cancer research?
How is it funded, and why does it feel like progress is so slow?
From the "bench" in the lab to the "bedside" in the clinic, this episode explores the often-misunderstood journey of a potential cancer treatment. They demystify everything from government and pharmaceutical funding to the difference between basic science and clinical trials.
👨⚕️Dr. Concannon provides a rare, inside look into the day-to-day realities of a physician-scientist's lab, revealing the immense costs, endless hours, and high-stakes decisions that shape the future of oncology.
🎗️Samantha offers her invaluable perspective as a patient, highlighting the emotional and systemic barriers that the community faces.
This episode is a must-listen for anyone seeking to understand the inner workings of the cancer industry, the real reason behind a drug's long development, and how patient advocacy is a critical driver of hope and progress.
Key Takeaways:
Who funds cancer research?
The biggest barrier to progress is cost.
A "promising" idea is a big risk.
The difference between mice and humans.
Patient advocacy is crucial.
Chapters
(00:00) Introduction to Cracking Cancer
(02:16) Major Players in Cancer Research
(08:23) The Role of Funding in Cancer Research
(13:54) Challenges and Costs in Cancer Research
(23:21) Evaluating Promising Cancer Therapies
(30:00) The Complexity of Cancer Research Trials
(40:30) Challenges in Clinical Trials
(50:10) The Role of Mice in Cancer Research
(58:38) Funding and Financial Risks in Cancer Research
(01:10:27) Concluding Thoughts and Future Directions
The Cracking Cancer Podcast's main focus is to further education about cancer and its effects on people and communities through continued discussion and to raise funds for the continued research of cancer treatments and positive outcomes. All raised proceeds go directly to the continued upkeep of this podcast and cancer research. To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org
Attributions
The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License
X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X
IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos

Thursday Aug 21, 2025
Thursday Aug 21, 2025
In this episode, Dr. Kyle Concannon and patient advocate Samantha Murrell dive deep into lung cancer. They discuss the basics of lung cancer, how it forms, common misconceptions, and the differences between small cell and non-small cell lung cancers. They also cover the symptoms and signs of lung cancer, how it is diagnosed, the importance of molecular testing, and various treatment options, including chemotherapy, immunotherapy, targeted therapies, and more. This comprehensive discussion aims to bring clarity, hope, and practical information to anyone affected by lung cancer.
Chapters
(00:00) Introduction to Cracking Cancer
(01:42) How Lung Cancer Forms and Spreads
(04:40) Lung Nodules: What They Mean and When to Worry
(07:17) Primary Tumors in the Lungs: Size and Spread
(11:33) Types of Lung Cancer: Small Cell vs. Non-Small Cell
(23:04) Symptoms and Signs of Lung Cancer
(34:40) Diagnosing Lung Cancer: Scans and Biopsies
(58:13) Exploring Treatment Options
(01:08:44) Conclusion and Next Steps
The Cracking Cancer Podcast's main focus is to further education about cancer and its effects on people and communities through continued discussion and to raise funds for the continued research of cancer treatments and positive outcomes. All raised proceeds go directly to the continued upkeep of this podcast and cancer research. To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org
Attributions
The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License
X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X
IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos

Thursday Aug 14, 2025
Thursday Aug 14, 2025
In this episode of Cracking Cancer, host Dr. Kyle Concannon is joined by Heidi Onda, a lung cancer survivor and founder of The White Ribbon Project. After going to the doctor with concerns of ovarian cancer, Heidi's world was rocked when they instead found Stage 3 Lung Cancer. Looking for support in the Lung Cancer community, Heidi was shocked to find the community lacked key representation, and a symbol to flock around within the medical community.
Today, they discuss Heidi's journey from diagnosis to advocacy, the creation and growth of The White Ribbon Project, and how it aims to provide support and raise awareness for lung cancer patients. Heidi shares her personal story, the challenges of battling lung cancer stigma, and the importance of community, collaboration, and advocacy in improving outcomes for all affected by the disease. Hear about the impact of grassroots movements and learn how to get involved in creating positive change in the cancer community.
Chapters
(00:00) Introduction to Cracking Cancer
(01:32) The Shocking Diagnosis and Initial Reactions
(08:55) The Birth of the White Ribbon Project
(12:43) Challenges and Triumphs in Advocacy
(20:54) Building a Supportive Community
(26:27) Personal Reflections and Future Hopes
(34:02) Pharmaceutical Donations and Stigma
(38:40) The Role of Celebrities and Media
(42:02) Fundraising and 501(c)(3) Status
(53:21) The White Ribbon Project's Mission
(01:02:11) Conclusion and Final Thoughts
The Cracking Cancer Podcast's main focus is to further education about cancer and its effects on people and communities through continued discussion and to raise funds for the continued research of cancer treatments and positive outcomes. All raised proceeds go directly to the continued upkeep of this podcast and cancer research. To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org
Attributions
The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License
X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X
IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos

Thursday Aug 07, 2025
Thursday Aug 07, 2025
Dr. Kyle Concannon, joined by co-host JJ Singleton, dives deep into the sensitive topic of male fertility affected by cancer treatments. Joined by Dr. Cathy Ang, a medical oncologist from Vanderbilt Ingram Cancer Center, and colorectal cancer survivor JJ Singleton, they discuss the often-overlooked issue of fertility planning for cancer patients. JJ shares his personal journey and the emotional and financial barriers he faced, while Dr. Ang provides insights into the clinical side of male fertility preservation. Tune in for an honest and informative discussion aimed at empowering cancer patients and breaking stigmas around male fertility.
Chapters
(00:00) Introduction to Cracking Cancer
(01:44) The Importance of Discussing Male Fertility
(05:47) The Emotional Impact of Fertility Issues
(09:48) Medical Perspectives on Fertility and Cancer Treatment
(17:38) Challenges in Addressing Male Fertility
(21:59) Mental Health and Coping Strategies
(27:48) Challenges in Discussing Sperm Banking
(38:19) Financial and Emotional Hurdles
(43:22) Barriers and Solutions in Oncology Clinics
(48:51) Final Thoughts and Advice
The Cracking Cancer Podcast's main focus is to further education about cancer and its effects on people and communities through continued discussion and to raise funds for the continued research of cancer treatments and positive outcomes. All raised proceeds go directly to the continued upkeep of this podcast and cancer research. To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org
Attributions
The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License
X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X
IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos

Thursday Jul 31, 2025
Thursday Jul 31, 2025
When you hear that someone is being treated for cancer, the immediate thought can often be about chemotherapy, and the horror story that you've heard so many times. Nausea, sores, suffering, all in hopes to live. In this episode, we dive into platinum-based chemotherapy with insights from clinical pharmacist Whitney Lewis and lung cancer patient advocate Samantha Murell. You'll learn about the function, history, and impact of platinum chemotherapy, including cisplatin, carboplatin, and oxaliplatin. Discover common side effects, coping strategies, and real-world experiences from someone who's been through the treatment. Join us as we demystify chemotherapy, discuss supplement interactions, and offer vital advice for those beginning their cancer treatment journey.
Chapters
(00:00) Introduction to Cracking Cancer
(01:17) Understanding Platinum Chemotherapy
(04:51) Patient Experience and Common Questions
(14:02) Types of Platinum Chemotherapy
(19:09) Side Effects and Management
(39:42) Understanding Chemotherapy's Impact on the Immune System
(44:24) The Importance of Communication with Your Care Team
(56:32) Addressing Misconceptions and Best Practices
(01:19:19) Conclusion and Closing Remarks
The Cracking Cancer Podcast's main focus is to further education about cancer and its effects on people and communities through continued discussion and to raise funds for the continued research of cancer treatments and positive outcomes. All raised proceeds go directly to the continued upkeep of this podcast and cancer research. To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org
Attributions
The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License
X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X
IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos

Thursday Jul 24, 2025
Thursday Jul 24, 2025
With over 1.3 million U.S. citizens alone being in the military, it is without a doubt a number of them will inevitably be faced with a cancer diagnosis during their active status. Today, we speak with Commander Bill Phillips, a retired military aviator, and co-host Samantha, a military spouse, to disucss the unique challenges faced by cancer patients in the military.
The discussion focuses on how a military mindset can help in preparing and proceeding through cancer treatment. Learn about the emotional and logistical hurdles, the value of peer support, and practical advice for military personnel and their families dealing with cancer. Discover how to adapt, overcome, and find purpose even in the face of such a daunting diagnosis.
Chapters
(00:00) Introduction to Cracking Cancer
(02:04) Bill's Experience with Military Healthcare
(04:55) Navigating Delays and Challenges
(12:46) Samantha's Story and Military Support
(20:46) Finding Purpose and Advocacy
(29:32) Support Systems and Resources
(36:11) Impact on Military Careers
(41:37) The Importance of Adaptability and Resilience
(54:03) The Role of Coaching in Cancer Care
(01:04:18) Resources for Military Families Facing Cancer
The Cracking Cancer Podcast's main focus is to further education about cancer and its effects on people and communities through continued discussion and to raise funds for the continued research of cancer treatments and positive outcomes. All raised proceeds go directly to the continued upkeep of this podcast and cancer research. To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org
Attributions
The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License
X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X
IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos

Thursday Jul 17, 2025
Thursday Jul 17, 2025
Joined by prostate cancer patient Tim Fitzgerald and medical oncologist Dr. Justin Lebenthal, Dr. Kyle Concannon discusses the complexities of prostate cancer and dives into the general community perception that prostate cancer is not a "big deal".
Dr. Lebenthal explains the basics of prostate cancer, the function of the prostate, and the importance of PSA screening. Tim Fitzgerald shares his personal journey, from diagnosis to treatment and ongoing management, including the impact on his daily life and mental health. They discuss the challenges of living with prostate cancer, the pros and cons of various treatments, and the importance of maintaining quality of life. The episode also touches on the advancements in prostate cancer treatment and the role of AI in improving diagnosis and management.
To hear more about Tim's journey with prostate cancer, check out his own podcast here.
Chapters
(00:00) Introduction to Cracking Cancer
(01:48) Understanding Prostate Cancer
(04:48) Tim Fitzgerald's Prostate Cancer Journey
(10:01) The Emotional and Psychological Impact of Cancer
(21:13) The Importance of Early Detection and PSA Testing
(29:41) Prostate Cancer Staging and Treatment Options
(38:29) A Life-Changing Call
(42:09) Challenges of Chemotherapy
(50:18) Screening and Overdiagnosis
(55:33) Living with Prostate Cancer
(01:14:10) Final Thoughts and Support Networks
The Cracking Cancer Podcast's main focus is to further education about cancer and its effects on people and communities through continued discussion and to raise funds for the continued research of cancer treatments and positive outcomes. All raised proceeds go directly to the continued upkeep of this podcast and cancer research. To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org
Attributions
The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License
X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X
IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos

Thursday Jul 10, 2025
Thursday Jul 10, 2025
Dr. Kyle Concannon engages in an insightful conversation with cancer patients JJ Singleton and Bill Phillips about how men uniquely experience cancer. Covering topics such as personal identity, coping mechanisms, and the impact on masculinity, this discussion delves into the emotional and psychological challenges faced by men during their cancer journey.
The episode also highlights the transformative work being done by the KFG Project, a nonprofit founded by Bill Phillips, aimed at providing professional support to patients and caregivers. Tune in to hear real stories, practical advice, and life-changing perspectives.
Want to learn more about Bill's KFG project? Home | KFG Project
Chapters
(00:00) Introduction to Cracking Cancer
(04:00) Bill's Story: Shock and Coping Mechanisms
(07:17) The Male Experience: Resilience and Vulnerability
(10:18) Compartmentalization: Coping Strategies
(22:32) Finding Purpose: The KFG Project
(42:40) The Mental and Physical Connection
(49:19) Incontinence and Radiation Side Effects
(01:14:11) The Importance of Open Dialogue
(01:22:04) Introducing the KFG Project
(01:28:12) Final Thoughts and Closing Remarks
The Cracking Cancer Podcast's main focus is to further education about cancer and its effects on people and communities through continued discussion and to raise funds for the continued research of cancer treatments and positive outcomes. All raised proceeds go directly to the continued upkeep of this podcast and cancer research. To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org
Attributions
The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License
X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X
IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos

Thursday Jul 03, 2025
Thursday Jul 03, 2025
In this episode, we delve into the complex topic of cancer remission. What does 'remission' really mean? How does it differ across different stages of cancer? Dr. Concannon and Samantha discuss their experiences and provide insights into the terminologies like complete response, partial response, stable disease, and no evidence of disease (NED).
We also tackle the emotional rollercoaster that comes with scans and tumor monitoring, while debunking common misconceptions around alternative therapies. Whether you're a patient, caregiver, or curious learner, this episode aims to bring clarity and hope in navigating the fight against cancer. For more information, visit crackingcancer.org.
Chapters
(00:00) Introduction to Cracking Cancer
(06:46) Complete Response vs. Partial Response
(15:15) The Reality of Stable Disease
(21:04) The Concept of Cancer 'Sleeping'
(30:56) Understanding Treatment Timelines
(35:59) The Role of the Immune System
(42:04) Emotional Rollercoaster of Monitoring
(47:50) Misconceptions About Remission
(51:20) Caution with Alternative Therapies
(59:09) Final Thoughts and Advice
The Cracking Cancer Podcast's main focus is to further education about cancer and its effects on people and communities through continued discussion and to raise funds for the continued research of cancer treatments and positive outcomes. All raised proceeds go directly to the continued upkeep of this podcast and cancer research. To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org
Attributions
The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License
X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X
IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos

Thursday Jun 26, 2025
Thursday Jun 26, 2025
Dr. Kyle Concannon dives into the intricate world of pulmonary nodules with real patient Ashley Holt and pulmonologist Dr. Alex Dragnich. They talk about the essential questions to ask after a nodule is detected, the diagnostic processes involved, and the emotional journey of discovering and treating potential lung cancer.
Ashley shares her personal experience from an incidental finding to undergoing a lobectomy, while Dr. Dragnich explains what a pulmonary nodule is, the likelihood of it being cancerous, and the importance of monitoring and second opinions. This episode offers invaluable insights into empowering oneself with information and advocating for better care in the fight against cancer.
Chapters:
(00:00) Introduction to Cracking Cancer
(04:06) Understanding Pulmonary Nodules
(09:11) Risk Factors and Monitoring Lung Nodules
(28:42) Biopsy Procedures and Risks
(37:00) Understanding Cancer Risk in Lung Nodules
(41:47) Diagnosis and Initial Reactions
(51:05) Surgical Interventions and Recovery
(58:29) The Importance of Second Opinions
(01:04:49) Final Thoughts and Advice for Patients
The Cracking Cancer Podcast's main focus is to further education about cancer and its effects on people and communities through continued discussion and to raise funds for the continued research of cancer treatments and positive outcomes. All raised proceeds go directly to the continued upkeep of this podcast and cancer research. To find out more about supporting the show and research endeavors, please go to the following website: www.crackingcancer.org
Attributions
The music track - Progression Pulse - is provided by Denys Brodovskyi through the Attribution 4.0 International License
X: (1) Cracking Cancer Podcast (@Cracking_Cancer) / X
IG: Cracking Cancer (@crackingcancerpodcast) • Instagram photos and videos






